Effects of sodium hypochlorite and ozone on healing of intestinal
anastomosis in simulated strangulation colorectal obstruction.
Smolensk State Medical Academy.
Strangulation colorectal obstruction was modeled in 60
Wistar rats. Necrotic segment of the intestine was resected under
conditions of peritonitis and end-to-end intestinal anastomosis was
performed on a PCV catheter conducted through the anus. Sodium
hypochlorite and ozone solution were used for sanitation of the
abdominal cavity and intestinal lavage, and the intestinal anastomosis
was coated with Ozonide (ozonized oil). The use of physicochemical
methods notably reduced the incidence of postoperative pyoinflammatory
complications, incompetence of intestinal anastomosis sutures, and
PMID: 15085259 [PubMed - indexed for MEDLINE]